🧪 eGFR Calculator

Estimated Glomerular Filtration Rate – assess kidney function using race‑free CKD‑EPI 2021, MDRD, and pediatric Schwartz equations.
Used by nephrologists, primary care physicians, and pharmacists. 100% client‑side, private.

🩺 Kidney function 📊 CKD staging 🔒 No patient data stored

👤 Age (years)

Age in years

⚧ Sex assigned at birth

🧪 Serum Creatinine (mg/dL)

Standardized to IDMS-traceable assay

📏 Height for pediatric (cm)

Required for pediatric patients (1–16 years)

👶 Pediatric patient (1–16 years) – use Bedside Schwartz equation

📐 Calculation Method

CKD-EPI 2021 (race‑free, recommended)

MDRD Study (4‑variable)

Bedside Schwartz (pediatric only)

eGFR (mL/min/1.73 m²)

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📊 CKD Stage

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🩺 Interpretation

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💡 Clinical Note:

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📖 Understanding eGFR

Estimated Glomerular Filtration Rate (eGFR) is a key indicator of kidney function. It estimates how much blood passes through the glomeruli (filters) each minute. The NKF recommends the 2021 CKD-EPI race‑free equation as the most accurate method for estimating GFR in adults.[reference:0]

CKD-EPI 2021 Equation:

eGFR = 142 × min(Scr/κ, 1)ᵅ × max(Scr/κ, 1)⁻¹·²⁰⁰ × 0.9938ᴬᵍᵉ × 1.012 [if female]
κ = 0.7 (females) or 0.9 (males)
α = -0.241 (females) or -0.302 (males)[reference:1]

The Bedside Schwartz equation is the international standard for pediatric eGFR in children aged 1–16 years: eGFR = 0.413 × (height in cm / serum creatinine in mg/dL).[reference:2][reference:3]

✨ CKD Staging (KDIGO)

Stage	eGFR (mL/min/1.73 m²)	Kidney Function
G1	≥ 90	Normal or high
G2	60–89	Mildly decreased
G3a	45–59	Mild to moderate decrease
G3b	30–44	Moderate to severe decrease
G4	15–29	Severely decreased
G5	< 15	Kidney failure

Albuminuria (A1–A3) is also part of CKD staging according to KDIGO guidelines. This calculator provides GFR staging; albuminuria assessment should be added for complete risk stratification.[reference:4]

💡 Why Race‑Free Equations Matter

The 2021 CKD-EPI equation removed race as a variable because race-based adjustments were found to overestimate GFR in Black patients and were not biologically justified. This new equation provides more equitable kidney function assessment for all patients.[reference:5]

⚠️ Important Limitations

eGFR is an estimate, not a measured value.
Not validated for acute kidney injury, pregnancy, amputees, or extremes of muscle mass.
Confirm abnormal results with cystatin C-based eGFR or measured GFR if needed.
Always interpret with clinical context and albuminuria assessment.

❓ Frequently Asked Questions

The NKF and ASN recommend the 2021 CKD-EPI creatinine equation (race-free) for adults. It is more accurate than the MDRD equation, particularly at GFR > 60 mL/min/1.73 m².[reference:6] For children aged 1–16 years, the Bedside Schwartz equation is the international standard.

Normal eGFR in young adults is approximately 100–120 mL/min/1.73 m².[reference:7] Values above 90 with no other markers of kidney damage are considered normal. eGFR declines naturally with age.

No. All calculations are client-side. No information is sent to any server. Patient data remains private.